Exosomes are tiny vesicles, packaged in molecules that are released by cells in the body. They have been shown to be the primary mode of moving information between cells. They play a large role in the transportation of proteins, lipids and nucleic acids between cells in the body. They are produced throughout the body and play an essential role in the healing and repair of damaged tissues.
Because of its relative newness many biomedical applications regarding exosomal treatments are undergoing clinical assessments to test their viability and how they can help doctors assist patients in their goals.
What is the role of Exosomes within the body?
Exosomes’ primary role within the body appears to be communication. They can communicate whenever pathogens attack the body, which prompts the immune cells to activate T cells, which recognizes and attacks pathogens in the body. They have also been observed transporting RNA and proteins between the living cells within the body. The transportation of these two molecules alone make exosomes one of the most important extracellular vesicles within the body.
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How aging affects Exosome and Disease Control
The exosome that is produced by dead cells plays a vital role in the diagnosis of degenerative disease and cancer. They make it easy for the diagnosis of diseases at early stages, making treatment options possible even for cancer cases. However, as we get older, there is a shift in how the exosome functions in our body. For starters, the number of disease-promoting exosome increases in the body. The disease-promoting exosome, weakens our immune system naturally as we get older, making our bodies susceptible to infections.
A research that was done recently confirmed that the circulation of exosome in our body decreases with age. Moreover, how the exosome communicates with the cells also changes and becomes less efficient as we age. Generally, ageing and all the age-related diseases and disorders, are mainly tied to the exosome. The immune system slowly becomes impaired as a result of systemic inflammation of immune cells in the body.
An exosome has various ways of interacting with its target cells. For instance, it can interact with a cell through its receptors on the surface, or it can fuse directly with the cell membrane and release its cargo to the cell. However, the process of exosome interacting with cells is also more and more impaired as we get older.
Can they help with Erectile Dysfunction?
Platelet-rich plasma has been proven to help grow more tissue in the penile area. Moreover, by adding stem cells to the platelet-rich plasma, it brings in potent exosome, which is a powerful tool in promoting the growth of penile tissue.
The exosome therapy delivers proteins and RNA to your penile tissues. It forces the healthy cells to make proteins that will help in repairing the damaged cells in your penis. Their small nature enables them to travel through the body and pass boundaries that cannot be crossed by other cells, and carry proteins and platelets to your penile tissue.
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