The role that exosomal cells, which are sometimes referred to as blebs, minicells, or microvesicles, play in transmitting cellular information within the body has become one of the most exciting areas of medical research in recent years. These tiny vesicles facilitate communication from one cell to the other and are ideal for the delivery of lipid cargo and nucleic acids.
These bio-molecule particles range from 40 to 150 nanometers and form vesicles which each cell within a living organism can release.
Initially, they were perceived to be a medium of waste disposal in the body, but as time and research focused on their roles within the body, it has become increasingly clear just how extensively exosomes can affect normal everyday life.
What makes up an Exosomal cell?
Most cells within the body release exosomes under typical healthy circumstances. These exosomes are made up of phospholipids’ bilayer membrane which contains all the cargo found in each microvesicle.
The primary contents of these cells include contrasting forms of ribonucleic acid (RNA), lipids, genetic data, receptors, additional growth factors and cytokines. These phospholipids’ bilayer membrane is one of the primary structures of each cell membrane in the body.
These minicells also contain fluids that are released from the body’s cells and organs. Fluids play a significant role in facilitating cell to cell as well as organ to organ communication by transporting messenger molecules from one part of the body to the other.
This intracellular fluid also has an equally impressive part to play in the regular functions of many bodily systems. Saliva, blood plasma, amniotic fluid, bile, breast milk, mucus, saliva, serum, tears, and even urine has a unique purpose to play in regulating the normal functioning of your cells, organs and systems.
Why are Exosomes so important?
Despite knowing about these for well over 50 years, the value of exosomal molecules in science and medicine has only recently taken off in interest.
Because of their unique form, these extracellular vesicles have been identified as the key mediators of the cell to cell communication. By delivering distinct and unique packets of information saved in the form of lipids, proteins, and nucleic acids, exosomes can modulate many diverse functions within the body, such as wound healing, regeneration, and new growth.
You can read more about exosomal cell communication, function, and importance here.
The formation of Exosomal cells
Exosomes are formed by intraluminal vesicles (ILVs) which occurs within many, if not most of the cells within the body.
When a cell creates exosomal data, it begins by expanding its outer membrane to accommodate the additional fluids. Once this has been accomplished, the intraluminal vesicles within the cell begin to combine proteins and cellular material to create endosomes. As these endosomes develop, vesicles begin and continue to form over the membranes until exosomal cells, sometimes referred to as ILVS cells, are formed.
The formation of the ILVs requires the presence of a multivesicular body (MVB) and it is during the formation of these that lipids, RNAs, and proteins also begin to take shape.
One of the most distinct pathways in the multivesicular body is that of the ESCRT (Endosomal Sorting Complex Required for Transport) which is a multi-protein endowed channel whose functionality revolves around the selecting and transfer of precise bio-molecules into the ILVs. ESCRT can be used to manipulate different variables that can affect endocytosis and can have lipid rafts and protein receptors which can later be turned into ILVs.
By the end of this process, Exosomal cells have been formed.
What is Exosomes Therapy?
Therapies involving exosomal cells have steadily grown in interest over the last two decades, owing to their incredible versatility in treatment options. Exosomal therapy is one of the most exciting regenerative health solutions for mitigating or reversing many of the signs of aging and has shown great promise in the treatment of many degenerative diseases.
At HealthGAINS, we prescribe a unique customized therapy based on your individual health needs and goals.
While we use exosomal cells to treat a variety of conditions, we’ve found these cells have been able to offer a vast improvement in the quality of life for those suffering from erectile dysfunction (ED), hair loss, arthritis, joint, and back pain as well as generalized pain and inflammation.
Benefits of Exosomes Therapy
For many men, the underlying cause of their ED is a lack of blood flow substantial enough to maintain an erection. This can be caused by a variety of things, but what has been shown to be effective has been the use of exosomal therapy in conjunction with other medically supervised ED treatments.
One such treatment, GAINSWave®, uses a nonsurgical, noninvasive acoustic wave to break up deposits of plaque that prevent erections. During this clearing, a secondary process of micro cavitation occurs within the tissue, instigating the release of growth factors within the affected area. When used in concert with exosomes, these messenger cells can turbocharge the healing and growth process, effectively reversing ED for most men quickly and painlessly.
One of the most prescribed applications of exosomal therapy is the treatment of joint pain and inflammation. No matter if it is chronic or acute, management of pain is one of the most exciting uses for regenerative exosome therapy.
As mentioned above, exosomes carry vital information for the cells, most notably those of healing, growth and regeneration. When used as part of a comprehensive pain management therapy, many patients have been able to not only reduce the amount and frequency of their pain, they were also in many cases able to address the underlying causes of it.
Exosomes are incredible for fighting hair loss as they naturally instigate growth factors that can be used to restore thinning or lost hair. This therapy works to renew and regenerate the hair follicles and stimulate the production of keratin.
The ability of exosomes to restore cellular structures, repair, heal, and regenerate makes them ideal for many customized hair restoration therapies at HealthGAINS.
Treatment of Autoimmune Disease
Many of those with autoimmune diseases or disorders are prescribed exosomal therapy as a means of improving their immune response. Evidence seems to indicate that these tiny vesicles may play roles in both immune stimulation and tolerance since they are involved in many of the processes within the body such as immune signaling, inflammation and angiogenesis.
For example, patients with complications from Lyme disease can benefit from regenerative exosome therapy by using it to improve metabolism and inflammatory responses. Typically, these patients can expect to suffer when their mast cells begin to fail. Exosome therapy has been shown to help by managing the inflammatory responses, providing relief.
While exosomes can provide incredible relief to many, only a qualified medical professional from HealthGAINS will be able to perform the necessary diagnostic work to ensure your success with regenerative Exosome Therapy.
If you are interested in getting back to perfect health, have some nagging issues you’d like to address, or would simply like to see what it’s like to live a “great” life, then we encourage you to give us a call today at (305) 682-1818 to get started today.